
Removal of the testes or ovaries removes hormonal influences that appear to affect the adrenal gland. This is problematic because failing to spay females can result in life-threatening illness, while neutering males reduces odor and aggression. While the exact cause of this condition has not been determined, it is believed that spaying and neutering ferrets at an early age plays a role. Most affected ferrets are older than 2 years. What Causes Adrenal Gland Disease in Ferrets?Īdrenal gland disease is, unfortunately, a common disease of pet ferrets in the United States. Treatment may involve surgery or medication.

The most common clinical sign is hair loss.Adrenal gland disease usually affects adult ferrets (older than 2 years).
